@article {Dilokthornsakul1014作者= {Piyameth Dilokthornsakul和罗伯特·j·Valuck与诉Nair和约翰·r·Corboy和理查德·r·艾伦和乔纳森·d·坎贝尔},title ={多发性硬化患病率在美国商业保险人口},体积={86}={11},页面= {1014 - 1021}= {2016},doi = {10.1212 / WNL。出版商0000000000002469}= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:估计美国商业保险多发性硬化症(MS)每年的患病率从2008年到2012年半岛投注体育官网。方法:该研究是一个回顾性分析使用PharMetrics +,一个全国性的数据库覆盖了4200万我们代表的生活。时点患病率每年需要保险资格在一整年。我们主要年度女士识别算法需要住院声称编码ICD-9 340或340或1 MS-indicated门诊理赔编码ICD-9疾病修饰治疗要求。年龄调整年度发病率估计是使用美国人口普查数据外推到美国人口。结果:2012 MS患病率为149.2每100000个人(95 \ % {\ textendash}置信区间147.6 - 150.9)。患病率超过2008 {\ textendash} 2012是相一致的。女性参与者3.13倍女士患病率最高的是在45 {\ textendash} 49岁的参与者每100000人(303.5 [295.6 {\ textendash} 311.5])。东部地区人口普查记录患病率最高(192.1 [188.2 {\ textendash} 196.0]);西部地区人口普查记录患病率最低(110.7 [105.5 {\ textendash} 116.0])。美国每年2012 MS推断人口403630(419833年387445 {\ textendash})。Conclusions: MS prevalence rates from a representative commercially insured database were higher than or consistent with prior US estimates. For further accuracy improvement of US prevalence estimates, results should be confirmed after validation of MS identification algorithms, and should be expanded to other US populations, including the government-insured and the uninsured.CI=confidence interval; COMIRB=Colorado Multiple Institute Review Board; DMT=disease-modifying therapy; ICD-9=International Classification of Diseases{\textendash}9; MS=multiple sclerosis}, issn = {0028-3878}, URL = {//www.ebmtp.com/content/86/11/1014}, eprint = {//www.ebmtp.com/content/86/11/1014.full.pdf}, journal = {Neurology} }