RT期刊文章SR电子T1多发性硬化的发生率在多个种族和族裔群体摩根富林明神经病学神经学乔FD Lippincott Williams &威尔金斯SP 1734 OP 1739 10.1212 / WNL。半岛投注体育官网80 0 b013e3182918cc2 VO 19 A1安妮特Langer-Gould A1 Sonu m . Brara A1布兰登·e·Beaber A1剑l .张年2013 UL //www.ebmtp.com/content/80/半岛投注体育官网19/1734.abstract AB目的:确定多发性硬化症(MS)的发病率不同的种族在一个多民族,人口基数。方法:我们进行了一项回顾性队列研究超过900万人年观察从多民族社区的成员南加州Kaiser Permanente健康计划从1月1日,2008年到2010年12月31日。女士的发生率和风险比率比较发病率之间的种族/民族使用泊松回归计算。结果:我们发现496例新诊断为女士见过麦当劳的标准。诊断的平均年龄为41.6岁(范围8.6 - -78.3年),70.2%是女性。黑人女性的优势更明显(79.3%)比白人、拉美裔和亚洲患者MS(分别为67.8%、68.1%和69.2%;p = 0.03)。高女士在黑人的发病率(10.2,95%可信区间[CI] 8.4 - -12.4;p < 0.0001),降低在西班牙裔(2.9,95%可信区间2.4 - -3.5;p < 0.0001)和亚洲(1.4,95%可信区间0.7 - -2.4;p < 0.0001)比白人(6.9,95%可信区间6.1 - -7.8)。 Black women had a higher risk of MS (risk ratio 1.59, 95% CI 1.27–1.99; p = 0.0005) whereas black men had a similar risk of MS (risk ratio 1.04, 95% CI = 0.67–1.57) compared with whites.Conclusions: Our findings do not support the widely accepted assertion that blacks have a lower risk of MS than whites. A possible explanation for our findings is that people with darker skin tones have lower vitamin D levels and thereby an increased risk of MS, but this would not explain why Hispanics and Asians have a lower risk of MS than whites or why the higher risk of MS among blacks was found only among women.CI=confidence interval; CIS=clinically isolated syndrome; ICD-9=International Classification of Diseases, ninth revision; MS=multiple sclerosis

map