% 0期刊文章%安妮特Langer-Gould % Sonu m . Brara %布兰登·e·Beaber %剑l .张% T多发性硬化的发生率在多个种族和族裔群体% D R 10.1212 / WNL 2013%。0 b013e3182918cc2 % 半岛投注体育官网J神经病学% P 1734 - 1739 X % V 80% N 19%目的:确定多发性硬化症(MS)的发病率不同的种族在一个多民族,人口基数。方法:我们进行了一项回顾性队列研究超过900万人年观察从多民族社区的成员南加州Kaiser Permanente健康计划从1月1日,2008年到2010年12月31日。女士的发生率和风险比率比较发病率之间的种族/民族使用泊松回归计算。结果:我们发现496例新诊断为女士见过麦当劳的标准。诊断的平均年龄为41.6岁(范围8.6 - -78.3年),70.2%是女性。黑人女性的优势更明显(79.3%)比白人、拉美裔和亚洲患者MS(分别为67.8%、68.1%和69.2%;p = 0.03)。高女士在黑人的发病率(10.2,95%可信区间[CI] 8.4 - -12.4;p < 0.0001),降低在西班牙裔(2.9,95%可信区间2.4 - -3.5;p < 0.0001)和亚洲(1.4,95%可信区间0.7 - -2.4; p < 0.0001) than whites (6.9, 95% CI 6.1–7.8). Black women had a higher risk of MS (risk ratio 1.59, 95% CI 1.27–1.99; p = 0.0005) whereas black men had a similar risk of MS (risk ratio 1.04, 95% CI = 0.67–1.57) compared with whites.Conclusions: Our findings do not support the widely accepted assertion that blacks have a lower risk of MS than whites. A possible explanation for our findings is that people with darker skin tones have lower vitamin D levels and thereby an increased risk of MS, but this would not explain why Hispanics and Asians have a lower risk of MS than whites or why the higher risk of MS among blacks was found only among women.CI=confidence interval; CIS=clinically isolated syndrome; ICD-9=International Classification of Diseases, ninth revision; MS=multiple sclerosis %U //www.ebmtp.com/content/neurology/80/19/1734.full.pdf