% 0期刊文章%布鲁克D康威Kleven %一个布莱恩Labus Lung-Chang Chien % % %乍得L十字亚伦丽贝卡•兰德尔Ritter % %一个查尔斯Bernick Arturo蒙特斯% % T纵向变化区域的脑容量和认知专业战士创伤性脑病综合症% D R 10.1212 / WNL 2023%。0000000000207594 % J半岛投注体育官网神经病学% P 10.1212 / WNL。0000000000207594 X %的背景和目的:由于电流限制在诊断慢性创伤性脑病(CTE)临床创伤性脑病综合征(te)已被建议作为疑似CTE的临床表现。本研究旨在确定是否有一个关联的临床诊断测试和随后的时间认知或MRI体积下降的措施。方法:这是一个中等职业运动员的大脑健康研究的分析,包括积极的和退休的专业战士34岁以上的。所有运动员被裁决为te正面(te +)或负面(te)根据2021年临床标准。一般线性混合模型被用来比较MRI区域脑容量和团体之间的认知能力。结果:共有130名战士见到入选标准共识会议。现年52岁的这些战士(40%)被裁决为测试工程师+。经颅电刺激运动员+诊断老年教育和有显著降低。统计上显著的交互和群体间的总平均差异被发现在所有MRI体积测量众多测试+相比,组。体积变化的速度表示显著增加更多的横向(估计= 5196.65;95% CI = 2642.65, 7750.66)和下侧脑室(估计= 354.28; 95% CI= 159.90, 548.66) and a decrease for the hippocampus (estimate = -385.04, 95% CI= -580.47, -189.62), subcortical gray matter (estimate= -4641.08; 95% CI= -6783.98, -2498.18), total gray matter (estimate= -26492.00; 95% CI= -50402.00, -2582.32), and posterior corpus callosum (estimate= -147.98; 95% CI= -222.33, -73.62). Likewise, the rate of cognitive decline was significantly greater for reaction time (estimate= 56.31; 95% CI= 26.17, 86.45) and other standardized cognitive scores in the TES+ group.Discussion: The 2021 TES criteria clearly distinguishes group differences in the longitudinal presentation of volumetric loss in select brain regions and cognitive decline among professional fighters 35 and over. This study suggests that a TES diagnosis may be useful in professional sports beyond football, such as boxing and mixed martial arts. These findings further suggest that the application of TES criteria may be valuable clinically in predicting cognitive decline. %U //www.ebmtp.com/content/neurology/early/2023/06/28/WNL.0000000000207594.full.pdf