PT -期刊文章盟安德鲁·j·所罗门AU -露丝安上盟尚Viswanathan AU -豪尔赫Correale AU -梅林达Magyari盟-尼尔·p·罗伯逊盟迪安娜·r·塞勒非盟-温迪凯盟-林赛Rechtman盟Eunchan Bae AU -罗素筱原尚盟瑞秋王盟乔安娜Laurson-Doube盟——安妮·赫尔姆TI -全球障碍的诊断多发性硬化症:多发性硬化症国际联合会的数据阿特拉斯女士,第三版- 10.1212 / WNL的援助。0000000000207481 DP - 2023年6月15日TA -神经病半岛投注体育官网学PG - 10.1212 / WNL。0000000000207481 4099 - http://n.半岛投注体育官网neurology.org/content/early/2023/06/15/WNL.0000000000207481.short 4100 - //www.ebmtp.com/content/early/2023/06/15/WNL.0000000000207481.full AB -背景和目标:最近的数据表明增加全球流行的多发性硬化症(MS)。早期诊断的MS减少残疾调整生命年的负担和相关医疗费用。然而诊断延误坚持照顾女士,甚至与强大的资源,在国家医疗保健系统全面的注册中心,女士subspecialist转诊网络。全球患病率和加速女士障碍诊断的特点,尤其是在resource-restricted地区,还没有被广泛的研究。最近修正MS诊断标准展示潜力促进早期诊断,但全球实现在很大程度上仍是个未知数。方法:多发性硬化症国际联合会(MSIF)第三版的阿特拉斯女士是一个调查,评估当前的全局状态的诊断包括:采用MS诊断标准;障碍诊断的病人,卫生保健提供者,和卫生系统;和存在的国家指导方针或国家标准速度的诊断。结果:协调人来自107个国家(占世界人口大约82%的),参与。 83% reported at least one “major barrier” to early MS diagnosis. The most frequently reported barriers included: “lack of awareness of MS symptoms among general public” (68%) “lack of awareness of MS symptoms among healthcare professionals” (59%), and “lack of availability of “healthcare professionals with knowledge to diagnose MS” (44%). One-third reported lack of “specialist medical equipment or diagnostic tests”. 34% reported use of only 2017 McDonald criteria (McD-C) for diagnosis and 79% reported 2017 McD-C as the “most commonly used criteria”. 66% reported at least one barrier to adoption of 2017 McD-C, including “neurologists lack awareness or training” by 45%. There was no significant association between national guidelines pertaining to MS diagnosis or practice standards addressing speed of diagnosis and the presence of barriers to early MS diagnosis and implementation of 2017 McD-C.Discussion: This study finds pervasive consistent global barriers to early diagnosis of MS. While these barriers reflected a lack of resources in many countries, the data also suggest that interventions designed to develop and implement accessible education and training can provide cost-effective opportunities to improve access to early MS diagnosis.