以便% % 0期刊文章%费朗德鲍曼,塞德里克% Aron,奥利弗% Vignal, jean - pierre %乔纳斯,雅克·% Tyvaert,路易丝% Colnat-Coulbois,苏菲% Koessler医生,Laurent %美拉德,路易% T颅内关联的头皮脑电图猝发的排放基于同步Stereo-EEG录音% D R 10.1212 / WNL 2023%。0000000000207135 % J半岛投注体育官网神经病学% P 10.1212 / WNL。0000000000207135 X %的背景和目的:它仍然是未知的猝发的头皮脑电图在多大程度上可以准确预测intra-cerebral癫痫发作的本地化耐药性癫痫的术前评估。在这项研究中,我们旨在定义均匀猝发的头皮脑电图(基于他们的第一次发作的异常)和评估他们使用同时记录头皮脑电图和Stereo-EEG本地化值。方法:我们回顾性包括连续耐药局灶性癫痫患者曾同时stereo-EEG和头皮脑电图记录至少一发作,在南希癫痫学单元中,法国。我们分析每个病人发作和层次聚类分析用于集团类似发作在头皮脑电图资料,然后进行了描述性分析的intra-cerebral关联。结果:在本研究中我们招收了129名病人。层次聚类分析显示六概要头皮脑电图第一次修改。没有特定于单个intra-cerebral本地化。“正常脑电图”和“模糊脑电图”集群(早期肌肉工件)只包含五个病人,与没有优惠intra-cerebral本地化。“时间放电”集群(46例)表现为θ或δ排放于同侧前颞头皮电极和与中央的优惠时间intra-cerebral本地化。“后放电”集群(n = 42)同侧或对侧的特点是后节奏α排放或慢波头皮和对应优惠时间定位。 However, this profile was the statistically most frequent scalp EEG correlate of occipital and parietal seizures. The “diffuse suppression” cluster (n=9) was characterized by a bilateral and diffuse background activity suppression on scalp and corresponded to mesial, and particularly insulo-opercular, localization. Finally, the “frontal discharge” cluster (n=22) was characterized by bilateral frontal rhythmic fast activity or pre-ictal spike on scalp and corresponded to preferential ventrodorsal frontal intra-cerebral localizations.Discussion: Hierarchical cluster analysis identified six seizure profiles regarding the first abnormality on scalp EEG. None of them was specific of a single intra-cerebral localization. Nevertheless, the strong relationships between the “temporal”, “frontal”, “diffuse suppression” and “posterior” profiles and intra-cerebral discharges localizations may contribute to hierarchize hypotheses derived from ictal scalp EEG analysis regarding intra-cerebral seizure onset. %U //www.ebmtp.com/content/neurology/early/2023/03/24/WNL.0000000000207135.full.pdf