RT期刊文章SR电子T1连接之前血管内溶栓治疗中风患者更快的核心增长摩根富林明神经病学神经学乔FD Lippincott Williams &威尔金斯10.1212 SP / WNL。半岛投注体育官网0000000000207154 10.1212 / WNL。刘张0000000000207154 A1哈哈林A1郝A1飞凤A1陈陈A1 Chushuang陈A1安德鲁Bivard A1马克W帕森斯A1李刚年2023 UL //www.ebmtp.com/content/early/2023/03/24/WNL.0000000000207154.abstract半岛投注体育官网 AB背景和目标:它仍然是不确定的,要直接血管内血栓切除术(EVT)会导致相同的结果作为桥接静脉溶栓(溶)在急性缺血性患者。本研究旨在探讨缺血性核心增长率是否影响病人溶桥接后的结果与直接EVT。方法:这是一个回顾性队列研究基于国际中风灌注成像注册(激励)。它选择接受灌注CT在4.5小时内急性缺血性中风患者中风的发病。直接去EVT的患者相比,那些接受了桥接治疗EVT之前的早期。缺血性急性缺血性核心核心增长率估计的体积在灌注CT除以时间从发病到灌注CT,基于假设缺血性的线性增长模式的核心。核心增长率分为快速(> 15毫升/小时)和慢速(≤15毫升/小时),根据其与桥接诊断和预测的主要结果。主要的结果是0 - 2改良Rankin规模在3个月。次要结果包括血栓切除术成功再灌注所定义的修改在脑梗死的溶栓2酮,和时间从腹股沟穿刺到再灌注。结果:1221 EVT患者的启发,选择323例患者,其中82名患者接受直接EVT和241名患者接受溶桥接。桥接诊断与较高的患者良好的临床结果在核心快速增长(39% vs 7%直接EVT,比值比= 8.75 (1.96 - -39.1),p = 0.005),但患者的核心增长缓慢的差异则不显著(55% vs 55%直接EVT,比值比= 1.00 (0.53 - -1.87),p = 0.989)。 In patients with fast core growth, the bridging and direct EVT patients showed no difference in the reperfusion rate (80% vs. 76%, p=0.616). However, patients who received bridging IVT were more likely to achieve reperfusion earlier (the median groin to reperfusion time of 63.0 vs 94.0 minutes p=0.005).Discussion: Patients with fast core growth were more likely to benefit from bridging intravenous thrombolysis. This is likely because prior intravenous thrombolysis facilitates clot removal and thus reduces time to reperfusion.

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