泰的T1 -年龄和性别趋势在医学并发症急性缺血性中风后在美国摩根富林明-神经学乔-神经病学SP - e1282 LP - e1295做- 10.1212 / WNL。半岛投注体育官网0000000000206749六世- 100 - 12非盟-拉希德·艾哈迈德AU -卡尔Mhina盟卡兰菲利普AU - Smit d . Patel盟Ehimen Aneni AU - Chukwuemeka Osondu盟Oluwatomi Lamikanra AU - Emmanuel Oladele,非盟赤野光信案件Nnabuchi Anikpezie AU -卡伦·c·奥尔布赖特盟朱利叶斯·g·Latorre AU - Seemant Chaturvedi盟Fadar奥利弗Otite Y1 - 2023/03/21 UR - //www.ebmtp.com/content/100/12/e1282.abstract N2 -背景和目标来测试假设的年龄和性别患病率感半岛投注体育官网染(肺炎、败血症、尿路感染(UTI))和非传染性的(深静脉血栓形成(DVT),肺栓塞(PE),急性肾功能衰竭(ARF),急性心肌梗塞(AMI)和消化道出血[直布罗陀])并发症住院治疗急性缺血性中风(AIS)后增加在美国从2007年到2019年。方法:我们进行了一次连续横断面研究使用2007 - 2019年全国住院病人样本。主要AIS招生成年人(18岁以上),没有发现并发症使用国际疾病分类编码。我们量化的年龄/性别患病率并发症和负二项回归模型用于评估趋势随着时间的推移。结果5751601加权招生,51.4%是女性。25.1%的人至少1并发症。泌尿道感染(11.8%)、东盟地区论坛(10.1%)、肺炎(3.2%),和AMI(2.5%)是最常见的并发症,而脓毒症(1.7%)、直布罗陀海峡(1.1%)、深静脉血栓形成(1.2%),和PE(0.5%)是最普遍的。显著差异的并发症风险存在年龄/性别(男性泌尿道感染:18-39年2.1%;女性,80岁或更老的22.5%)。泌尿道感染(12.9% - -9.7%)和肺炎患病率(3.8% - -2.7%)下降,但ARF的增加了三倍(4.8% - -14%)在此期间≈2007 - 2019(所有p & lt;0.001)。 AMI (1.9%–3.1%), DVT (1.0%–1.4%), and PE (0.3%–0.8%) prevalence also increased (p < 0.001), but that of sepsis and GIB remained unchanged over time. After multivariable adjustment, risk of all complications increased with increasing NIH Stroke Scale (pneumonia: prevalence rate ratio [PRR] 1.03, 95% CI 1.03–1.04, for each unit increase), but IV thrombolysis was associated with a reduced risk of all complications (pneumonia: PRR 0.80, 85% CI 0.73–0.88; AMI: PRR 0.85, 95% CI 0.78–0.92; and DVT PRR 0.87, 95% CI 0.78–0.98). Mechanical thrombectomy was associated with a reduced risk of UTI, sepsis, and ARF, but DVT and PE were more prevalent in MT hospitalizations compared with those without. All complications except UTI were associated with an increased risk of in-hospital mortality (sepsis: PRR 1.97, 95% CI 1.78–2.19).Discussion Infectious complications declined, but noninfectious complications increased after AIS admissions in the United States in the last decade. Utilization of IV thrombolysis is associated with a reduced risk of all complications.AIS=acute ischemic stroke; AMI=acute myocardial infarction; ARF=acute renal failure; CKD=chronic kidney disease; DVT=deep venous thrombosis; GIB=gastrointestinal bleeding; HCUP=Healthcare Cost and Utilization Project; ICD-9=International Classification of Diseases, 9th Revision; ICD-10=International Classification of Diseases, 10th Revision; ICH=intracerebral hemorrhage; MT=mechanical thrombectomy; MV=mechanically ventilated; NIHSS=NIH Stroke Scale; NIS=Nationwide Inpatient Sample; PE=pulmonary embolism; PRR=prevalence rate ratio; UTI=urinary tract infection ER -