RT期刊文章SR电子T1气候变化和空气污染对神经健康、疾病和实践的影响JF神经病学JO神经病学FD Lippincott Williams & Wilkins SP 474 OP 483 DO 10.1212/WNL.0000000000201630半岛投注体育官网VO 100 IS 10 A1 Louis, Shreya A1 Carlson, Alise K. A1 Suresh, Abhilash A1 Rim, Joshua A1 Mays, MaryAnn A1 Ontaneda, Daniel A1 Dhawan, Andrew YR 2023 UL http://n.半岛投注体育官网neurology.org/content/100/10/474.abstract AB背景和目标尽管国际社会共同寻求在2100年之前将全球气温上升降低到1.5°C以下,但不可逆转的环境变化已经发生,随着地球变暖,这些变化将继续发生。当我们目睹地球变暖对人类健康的影响时,神经学家必须预测神经疾病的流行病学和发病率可能发生的变化。在这篇综述中,我们围绕与气候变化和神经健康相关的3个关键主题组织了我们的分析:极端天气事件和温度波动、新出现的神经传染病和污染物影响。在这些主题中,我们评估并回顾了最近与神经疾病和实践相关的文献。方法使用PubMed、OVID MEDLINE、EMBASE、PsycInfo和灰色文献中与气候变化、污染物和神经疾病相关的搜索词来确定研究。如果1990年至2022年期间发表的研究与人类发病率或患病率有关,并且是英文的,并且与神经系统疾病有关,那么这些研究将被纳入。结果我们共确定了364篇文章,归类为我们研究的3个关键主题:极端天气事件和温度波动(38项研究),新兴神经感染性疾病(37项研究)和污染物影响(289项研究)。纳入的研究强调了神经症状恶化与温度变异、蜱传感染与气候变暖、空气污染物与脑血管疾病发病率和严重程度之间的关系。极端温度和温度变异性都与中风发病率和严重程度、偏头痛、痴呆患者住院和多发性硬化症加重有关。暴露于空气污染物,特别是PM2.5和硝酸盐,与中风发病率和严重程度、头痛、痴呆风险、帕金森病和多发性硬化症加重有关。 Climate change has demonstrably expanded favorable conditions for zoonotic diseases beyond traditional borders and poses the risk of disease in new, susceptible populations. Articles were biased toward resource-rich regions, suggesting a discordance between where research occurs and where changes are most acute. As such, 3 key priorities emerged for further study: neuroinfectious disease risk mitigation, understanding the pathophysiology of airborne pollutants on the nervous system, and methods to improve delivery of neurologic care in the face of climate-related disruptions.ALS=amyotrophic lateral sclerosis; ED=emergency department; ICH=intracerebral hemorrhage; JEV=Japanese encephalitis virus; MS=multiple sclerosis; PD=Parkinson disease; TBE=tick-borne encephalitis; WHO=World Health Organization
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