TY - JOUR T1 -补充营养援助计划使用与记忆衰退之间的关联JF -神经学JO -神经学SP - e595 LP - e602 DO - 10.1212/WNL.0000000000201499半岛投注体育官网VL - 100 IS - 6 AU - Peiyi Lu AU - Katrina Kezios AU - Jongseong Lee AU - Sebastian Calonico AU - Christopher Wimer AU - Adina Zeki Al Hazzouri Y1 - 2023/02/07 UR - http://n.半岛投注体育官网neurology.org/content/100/6/e595.abstract N2 -背景和目标关于补充营养援助计划(SNAP)对老年人认知健康的影响的研究很少。我们试图在符合SNAP条件的美国老年人中研究SNAP使用与记忆力下降之间的关系。方法纳入1996年健康与退休研究中年龄在50岁以上且符合snap资格的参与者。参与者的SNAP资格是根据联邦标准构建的。参与者还自我报告了他们是否使用了SNAP。从1996年到2016年，使用综合评分对记忆功能进行两年一次的评估。为了解释SNAP使用者和非使用者之间预先存在的特征差异，我们使用人口统计学和健康协变量对SNAP使用的概率进行了建模。然后，我们使用线性混合效应模型，使用逆概率(IP)加权和倾向评分(PS)匹配技术，为SNAP用户和非用户的记忆功能轨迹建模。在所有模型中，我们都考虑了学习减员。Results Of the 3,555 SNAP-eligible participants, a total of 15.7% were SNAP users. At baseline, SNAP users had lower socioeconomic status and a greater number of chronic conditions than nonusers and were more likely to be lost to follow-up. Our multivariable IP-weighted models suggested that SNAP users had worse memory scores at baseline but slower rates of memory decline compared with nonusers (the annual decline rate is −0.038 standardized units [95% CI = −0.044 to −0.032] for users and −0.046 [95% CI = −0.049 to −0.043] for nonusers). Results were slightly stronger from the PS-matched sample (N = 1,014) (the annual decline rate was −0.046 units [95% CI = −0.050 to −0.042] for users and −0.060 units [95% CI = −0.064 to −0.056] for nonusers). Put in other words, our findings suggested that SNAP users had approximately 2 fewer years of cognitive aging over a 10-year period compared with nonusers.Discussion After accounting for preexisting differences between eligible SNAP users and nonusers as well as differential attrition, we find SNAP use to be associated with slower memory function decline.FPL=federal poverty level; HS=high school; HRS=Health and Retirement Study; IP=inverse probability; IPAW=IP attrition weight; IPTW=IP of treatment weight; PS=propensity score; SNAP=Supplemental Nutrition Assistance Program ER -