TY - JOUR T1 -珍珠&振动诱导的向下击眼球震颤:副肿瘤综合征中观察到的一个新的小脑信号JF -神经学JO -神经学SP - 43 LP - 46 DO - 10.1212/WNL.0000000000201466半岛投注体育官网VL - 100 IS - 1 AU - Kim Hyo-Jung AU - Hyun-Jae Kim AU - Jong-Hee Lee AU - Ji-Soo Kim Y1 - 2023/01/03 UR - http://n.半岛投注体育官网neurology.org/content/100/1/43.abstract N2 -对胸锁乳突肌或颅骨的振动刺激可能会增强前庭不对称并引起眼球震颤。我们报告一例宫颈癌副肿瘤性小脑变性患者血清抗ri抗体阳性,出现明显向下振动性眼震(VIN)。一名47岁女性发展自发的向上性眼球震颤,伴有或不伴有视觉注视。横向凝视和向上凝视时眼球震颤减少。收敛时,水平摇头约15秒后,乳突和前额受到振动刺激时,出现下行眼震。其他表现包括体位性下拍性眼震、平滑追踪受损、水平扫视过高和躯干性共济失调。在视频头脉冲测试中,两个水平半规管的前庭-眼反射(VOR)增益正常,但前半规管增加,后半规管减少。水平头部脉冲产生交叉耦合向下矫正扫视。 Given the asymmetric vertical VOR, downbeat VIN observed in our patient may be ascribed to enhanced upward bias of the VOR due to vestibulocerebellar dysfunction during the vibratory stimuli. Vibration-induced downbeat nystagmus should be added to the list of central vestibular signs and is likely due to cerebellar dysfunction. ER -
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