% 0期刊文章%弗朗西斯卡Puledda % Peter j .戈德比一个Christoph Schankin % % T雪视觉综合症% B 1100例的临床和表型描述% D R 10.1212 / WNL 2020%。0000000000008909 % J半岛投注体育官网神经病学% P e564-e574 % V 94% N 6% X客观验证当前的视觉标准雪和描述其共同使用大量临床表型数据库。方法:我们进行了网络调查的患者自我评价视觉雪(n = 1104),与完整的视觉雪综合症(n = 1061)或视觉雪没有综合症(n = 43)。我们还描述人口的患者(n = 70)迷幻剂坚持感觉障碍和视觉雪提出临床综合症。结果视觉雪人口平均年龄29岁,没有性别患病率。疾病通常开始在生命早期,≈40%的患者症状,只要他们能记得。最常出现的静态是黑色和白色。飞蚊症,和畏光最报道,后像额外的视觉症状。潜在类别分析表明,视觉雪并不与特定临床表型。严重程度可分为视觉症状的有经验。偏头痛和耳鸣有很高的患病率和独立关联到一个更严重的综合症。Conclusions Clinical characteristics of visual snow did not differ from the previous cohort in the literature, supporting validity of the current criteria. Visual snow likely represents a clinical continuum, with different degrees of severity. On the severe end of the spectrum, it is more likely to present with its common comorbid conditions, migraine and tinnitus. Visual snow does not depend on the effect of psychotropic substances on the brain.DSM-V=Diagnostic and Statistical Manual of Mental Disorders, 5th edition; HPPD=hallucinogen persisting perception disorder; VS=visual snow; VSS=visual snow syndrome %U //www.ebmtp.com/content/neurology/94/6/e564.full.pdf