The Cerebellum as the Central Hub of a Widespread Network in Essential Tremor
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Essential tremor (ET) is the most common movement disorder affecting an estimated 0.5 percent of people worldwide and 5 percent of adults older than 65 years.1 While ET is defined as tremor in the upper extremities, many patients also have other neurologic signs and symptoms, including tremor in other body parts, other motor symptoms, mild cognitive impairment, and neuropsychiatric symptoms. The neural mechanisms leading to ET and its associated motor and nonmotor symptoms remain largely unknown, and there is an ongoing debate surrounding whether ET should be classified as a neurodegenerative disorder.
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Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the editorial.
See page 644
- Received June 19, 2023.
- Accepted in final form June 29, 2023.
- © 2023 American Academy of Neurology
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