血管再通和初始可怜的侧枝循环确定担保招聘功能结果的影响。(P3.068)

文摘

背景:颅内leptomeningeal络脉是急性缺血性中风的一个重要补充反应(AIS)。然而,他们的进化之间的关系和对区域血流量的影响尚不清楚。在之前的研究中我们发现,延迟抵押品招聘与功能恶化是相关联的结果。我们通过各种因素分层和比较络脉预处理和第二天大脑的计算机断层血管造影(CTA)评估招聘和与功能的关系的结果在AIS患者静脉注射组织纤溶酶原激活物(IV-tPA)。方法:连续AIS病人预处理和第二天CTA和接收IV-tPA包括2010 - 2013年期间。络脉是由2个独立评估神经放射使用3——Miteff预定义的标准系统,马斯河系统和阿尔伯塔省20分担保规模的行程计划早期CT评分(方面)方法。好的结果在不到三被定义为改良Rankin规模(夫人)0 - 1的分数。明显的颅内出血是定义为一个流血署下降4或更多的点。结果:本研究包括209名患者。延迟抵押品招聘的后续CTA明显与死亡率增加有关2的3分级系统。 Collateral recruitment by ASPECTS system showed a trend for SICH. When stratified by the collateral grading on the initial CTA, all 3 scoring systems showed that poor collateral status on pre-treatment CTA with subsequent collateral recruitment was significantly associated with poor outcome and increased bleeding risk. When stratified by recanalization status of the primary occlusion, a lack of recanalization with collateral recruitment was associated with worse outcomes. No other factors significantly affected the functional outcomes. Conclusion: Delayed collateral recruitment results in higher mortality. Pre-thrombolysis collateral status and recanalization of the occluded artery are important determinants of how intracranial collateral evolution affects functional outcome in IV-tPA treated AIS patients.

披露:陈庆炎没有披露。绮博士没有披露。博士销量没有披露。表面没有披露博士。陈冯富珍没有披露。Rathakrishnan博士没有披露。博士很快就没有披露。Sharma博士没有披露。杨医生没有披露。