^99米Tc SPECT诊断颅底转移

文摘

摘要目的:评价SPECT诊断骨转移的作用在癌症患者颅底。背景:颅底转移常常引起临床症状特征。抗肿瘤治疗大多数病人症状改善或稳定。诊断可能是困难当神经影像学研究负(如发生在大约四分之一的患者)。病例报告显示骨SPECT在这些患者的作用。方法:我们回顾了所有患者的图表(1993 - 1996)在我们机构有颅底SPECT和至少一个神经成像研究(CT或MRI)临床疑似转移到头骨的基础。骨SPECT、CT和MRI是盲目地重新评估。结果:我们研究了56例,其中36个颅底转移。二十个病人其他原因的临床综合症,包括leptomeningeal和颅后窝转移,或良性的原因。在29日的36例(81%)与颅底转移,CT或MRI清楚地证明了病变。 Bone SPECT identified a hot spot in the appropriate region of the skull base in 28 of 36 patients (78%). All seven patients with negative CT or MRI had positive SPECT and four of these had a response to anti-tumor treatment. Conclusions: SPECT of the skull base can demonstrate lesions not identifiable by CT or MRI. In cancer patients suspected of having skull base metastasis, we recommend SPECT of the skull base when CT or MRI studies are negative.