2023年4月18日
;100 (16)
居民和其他部分
珍珠和Oy-sters:盐和胡椒,PLNTY耐药性癫痫
第一次出版2022年12月23日,
DOI: https://doi.org/10.1212/WNL.0000000000206782
埃尔玛·m·Paredes-Aragon
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
诺拉·a·AlKhaldi
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
豪尔赫·g·Burneo
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
唐纳德•李
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
李c盎
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
大卫·史蒂文
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
玛丽亚·麦克唐纳
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
Manuel Herrera-Aramburu
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
赛义德·m·Mirsattari
从临床神经科学(E.M.P.-A的部门。,J.G.B.,D.L.,L.C.A., D.S., S.M.M.), Department of Clinical Neurological Sciences and Oncology (M.M), Epidemiology and Biostatistics (J.G.B., D.S.), Pathology and Laboratory Medicine (L.C.A.), Medical Imaging (S.M.M.), Medical Biophysics (S.M.M.), and Psychology (S.M.M.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Department of Neurological Emergencies (E.M.P.-A.), National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Department of Neurology (N.A.A.), King Fahad University Hospital, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; and Epilepsy Department (M.H.-A.), Neurology Division, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
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文摘
耐药性癫痫,定义为两个或更多的失败抗癫痫药物达到夺取自由,负责2/3的癫痫病例。肿瘤负责多达15%的成人发病和多达6%的儿童癫痫发作。在这些肿瘤,俗称亚型DNET,报告,和低级星形细胞瘤常常怀疑。在肿瘤分类取得了新进展,基因肿瘤分类中发挥关键作用。多态低级神经上皮肿瘤的年轻(PLNTY)是一个高度由癫痫引起的肿瘤的亚型可能模仿低级神经胶质瘤但提供病理和基因的线索:oligodendroglioma-like蜂窝组件和渗透模式和强大CD34-immunopositive污渍。此外,一个关键发现是放射:单焦异常最好在MRI大脑天赋序列视为“盐和胡椒标志”和钙化感激CT头上。
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